La anemia hemolítica autoinmune (AHAI) es una alteración hematológica autoinmune producida por la síntesis de autoanticuerpos contra los antígenos propios. Estas representam as formas mais comuns de anemia hemolítica hereditária. .. quanto ao seu potencial carcinogênico67 em relação à população pediátrica. Recibido para publicación: Aceptado para publicación: Introducción. La anemia hemolítica microangiopática se describió por prime-.

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Ion transport pathology in the mechanism of sickle cell dehydration. We present the clinical cases of two children, aged 4 and7 respectively, with TTP, but with different evolution andtreatment. Key words autoimmune haemolytic anaemia, cold agglutinin disease, rituximab.

Care of patients with haemoglobin abnormalities: The role of hydroxyurea in the management of sickle cell disease. The etiology is still unknown,although different factors such as large von Willebrandfactor multimers and prostacyclin have been implicated. To improve our services and products, we use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer behavior.

Ela foi descrita por Linus Pauling et al. J Pediatr Rio J. Correction of the sickle cell mutation in embryonic stem cells.

Johnson C, Telen MJ. Braz J Med Biol Res.


Anemia hemolítica autoinmune por hemolisina bifásica | Anales de Pediatría (English Edition)

Biol Blood Marrow Transplant. The mechanism of action appears to be linked with the selective B-cell depletion and the lowering of autoantibody levels.

Sildenafil therapy in patients with sickle cell disease and pulmonary hypertension. Birgens H, Ljung R.

Pulmonary hypertension in sickle cell disease. Increased adhesive properties of neutrophils in sickle cell disease may be reversed by pharmacological nitric oxide donation.

Amer J, Fibach E. Genetic dissection and prognostic modeling of overt stroke in sickle cell anemia.

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Annals of Pediatrics is the Body of Scientific Expression of the Association and is the vehicle through which members communicate.

Oral chelators deferasirox and deferiprone for transfusional iron overload in thalassemia major: Diagnostic approach to hemoglobinopathies. Laboratorydata typically reveal hemolytic anemia, with schistocyteson the peripheral hemolktica, diminished serum haptoglobin,and thrombocytopenia.

Hepatic dysfunction hemoliticx sickle cell disease: Adhesion molecules and hydroxyurea in peditria pathophysiology of sickle cell disease. Tolentino K, Friedman JF. Clinically, it is characterized by microangiopathic hemolyticanemia, thrombocytopenia, neurologic abnormalities,fever and renal dysfunction. Therefore, properly designed clinical trials evaluating rituximab as salvage- and first-line-therapy for the treatment of AIHA and cold agglutinin disease are clearly warranted.

Int J Biochem Cell Biol. Clin Exp Pharmacol Physiol. Free Radic Biol Med. Hospital Xeral-Calde de Lugo.


Genetic insights into the clinical diversity of beta thalassaemia.

Recently, rituximab has been shown to be an alternative treatment option in children as well as in adults for relapsed and refractory autoimmune haemolytic anaemias and in patients who are medically unsuited for espenectomy. Full text is only aviable in PDF. Hemoliticx item has received. Corticoids represent the standard frontline therapeutic option for warm autoantibodies haemolytic anaemia.

Chronic sickle cell lung disease: You can change the settings or obtain more information by clicking here.

Modification of globin gene expression by RNA targeting strategies. J Womens Health Larchmt. Med Clin Barc, pp. Si continua navegando, consideramos que acepta su uso.

Chronic relapsing thrombotic thrombocytopenic purpura: HPLC studies in hemoglobinopathies. N Engl J Med.


Quek L, Thein SL. Established and experimental treatments for sickle cell disease. Carlos Gomes, cj. Bienvenido a siicsalud Contacto Inquietudes.

Population analysis of the alpha hemoglobin stabilizing protein AHSP gene identifies sequence variants that alter expression and function. Singh SP, Gupta S.